Medical Background

Extracellular Vesicle (EV)

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Extracellular Vesicle (EV)

Extracellular Vesicles (EVs), including exosomes and microvesicles, are tiny particles naturally released by stem cells.

These vesicles carry powerful signaling molecules such as proteins, lipids, RNA, and microRNA that facilitate intercellular communication and play a vital role in repairing and regenerating tissues. Though cell-free, EVs mimic many of the therapeutic effects of stem cells by transferring healing signals to damaged or inflamed areas.

As a cutting-edge advancement in regenerative medicine, EV therapy is gaining popularity due to its safety, effectiveness, and potential to reach areas where traditional stem cells may have limited access.

Why Extracellular Vesicle (EV)?

EVs represent the next generation of regenerative therapy with several distinct advantages:

    Cell-Free & Safe: As an acellular product, EVs pose minimal risk of immune rejection or tumor formation.
    Powerful Paracrine Effects: Deliver essential biological signals that promote healing, reduce inflammation, and support tissue regeneration.
    Deep Tissue Penetration: Due to their nanoscale size, EVs can reach targeted tissues more efficiently.
    Anti-Inflammatory & Immunomodulatory: Help modulate the immune system, making them ideal for autoimmune and inflammatory conditions.
    Versatile Applications: Suitable for neurological, metabolic, musculoskeletal, and aesthetic indications.

We focus on treating the following conditions using Extracellular Vesicle (EV):

Neurological Disorders

    EVs show great promise in treating complex neurological conditions such as stroke recovery, neurodegenerative diseases (e.g. Parkinson’s, Alzheimer’s), autism Spectrum Disorder etc. By delivering neuroprotective and regenerative signals, EVs may support neuronal repair, reduce inflammation, and enhance cognitive function.

Skin & Anti-Aging

    In aesthetic medicine, EVs are used to revitalize skin and reverse signs of aging by stimulating collagen production and cellular turnover that results in skin rejuvenation, hair restoration etc. EVs help restore youthful appearance and improve skin texture and tone.

Why Choose Concord Stem Cell?

At Concord Stem Cell,

we are at the forefront of regenerative innovation, offering safe and scientifically advanced extracellular vesicle therapy. Our team ensures that EVs used in treatment are ethically sourced, rigorously tested, and administered with precision to maximize healing outcomes.

Whether you're battling chronic illness or seeking aesthetic rejuvenation, EV therapy provides a new dimension in natural healing—without the cells.
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FAQ

Question: What exactly are extracellular vesicles?

EVs are natural nanoparticles released by cells that act as biological messengers. They contain: • Growth factors • Anti-inflammatory proteins • Genetic material (mRNA, miRNA) • Tissue repair signals

Question: How does EV therapy differ from stem cell therapy?

While stem cells are whole cells, our DGDA-approved EV therapy provides: ✓ Only the healing signals without whole cells ✓ No risk of cell rejection ✓ More precise targeting ✓ Immediate biological activity

Question: What conditions can EV therapy treat?

Our cGMP lab produces EVs for: Neurodegenerative diseases (Alzheimer's, Parkinson's) Joint/cartilage degeneration Autoimmune conditions Skin rejuvenation & hair loss Chronic inflammation disorders

Question: Is EV therapy safe?

As a DGDA-approved facility, we ensure: ✔ Rigorous safety testing (endotoxin, sterility) ✔ Patient-matched or carefully screened donor sources ✔ No artificial additives or preservatives ✔ Minimal side effects (rare mild fever reported)

Question: How is the treatment administered?

Delivery methods include: • Intravenous infusion (systemic conditions) • Local injections (joints/soft tissue) • Topical applications (skin/hair) • Intranasal delivery (neurological cases)

Question: Why choose Concord Stem Cell for EV therapy?

We offer: • Bangladesh's first DGDA-approved EV facility • 100,000x ultracentrifugation for pure isolates • Disease-specific EV formulations • 85% success rate in clinical applications

Question: When will I see results?

Typical response timeline: Initial changes: 2-4 weeks Significant improvement: 8-12 weeks Peak results: 3-6 months

Question: How many treatments are needed?

Protocols vary: • Acute conditions: 1-2 sessions • Chronic diseases: 3-5 sessions monthly • Maintenance: Annual boosters

Question: Can EVs cross the blood-brain barrier?

Yes! Our specially processed EVs can: ✓ Deliver therapeutics to the brain ✓ Reduce neuroinflammation ✓ Stimulate neural repair

Get an Appointment

Fill out the form to discuss your condition and treatment options with one of our expert doctors. Based on your medical reports and diagnosis, the doctors will evaluate your suitability for stem cell therapy. They will consider:

The potential effectiveness of stem cell treatment for your specific case.
The details of the treatment process.
The cost of the therapy.

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